Vaselinum aquosum cum sorbitano sesquioleate FTM-TMF

AVA cream (Vaselinum aquosum cum sorbitano sesquioleate FTM-TMF) is a semi-solid W/O emulsion primarily used as a protective and moisturizing dermal delivery system.
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Properties
A key characteristic of this base is its minimal formulation, consisting of only four components.
This limited composition offers a dual advantage:
- the risk of contact allergic reactions is minimized due to the absence of unnecessary excipients, fragrances, or preservatives
- its simple composition guarantees consistent pharmaceutical quality in extemporaneous preparations

AVA cream exerts its action through two complementary mechanisms:
- Occlusive effect: the fatty phase forms a protective lipid film on the skin, which counteracts transepidermal water loss (TEWL)
- Moisturizing effect: the wool fat alcohols penetrate the stratum corneum and promote local water retention, resulting in a pronounced emollient effect

Therapeutic application
Particularly indicated for dry skin conditions where a fatty, protective, and moisturizing base is required. The combination of occlusive and moisturizing properties makes it a widely used choice in both extemporaneous preparations and daily dermatological care.